Protein contained in many secretions such as saliva, tears, milk and colostrum and plays a key role in the fixation and transport of iron, a process necessary for the growth and development of pathogens. It has antimicrobial activity both bactericidal and fungicidal. In association with lactic ferments it hinders the growth of pathogenic bacteria without altering the growth of normal intestinal bacterial flora.

RSS The Journal of Pediatrics

  • Bleeding Severity and Phenotype in 22q11.2 Deletion Syndrome – A Cross-sectional Investigation April 6, 2021
    To prospectively quantify bleeding severity and elaborate hemorrhagic symptoms in children with 22q11.2 deletion syndrome (22q11DS) using two validated bleeding-assessment-tools (BATs), namely the pediatric bleeding questionnaire (PBQ) and the International Society on Thrombosis and Hemostasis BAT (ISTH-BAT). We additionally sought to compare subjects’ bleeding scores to unaffected first-degree family members.
    Priyal O. Patel, Adriane L. Baylis, Scott E. Hickey, Joseph Stanek, Richard E. Kirschner, Margaret L. Rand, Riten Kumar
  • Variation in Neonatal Transfusion Practice April 6, 2021
    To estimate the incidence of blood product transfusion, including red blood cells, platelets, and plasma, and characterize pre-transfusion hematologic values for infants during their initial hospitalization after birth.
    Ravi M. Patel, Jeanne E. Hendrickson, Marianne E. Nellis, Rebecca Birch, Ruchika Goel, Oliver Karam, Matthew S. Karafin, Sheila J. Hanson, Bruce S. Sachais, Ronald George Hauser, Naomi L.C. Luban, Jerome Gottschall, Cassandra D. Josephson, Martha Sola-Visner, NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P)
  • Thrombotic Microangiopathy Associated With Macrophage Activation Syndrome: A Multinational Study of 23 Patients April 6, 2021
    To describe the clinical characteristics, treatment, and outcomes of a multinational cohort of patients with macrophage activation syndrome (MAS) and thrombotic microangiopathy (TMA).
    Francesca Minoia, Jessica Tibaldi, Valentina Muratore, Romina Gallizzi, Claudia Bracaglia, Alessia Arduini, Elif Comak, Olga Vougiouka, Ralf Trauzeddel, Giovanni Filocamo, Antonio Mastrangelo, Concetta Micalizzi, Ozgur Kasapcopur, Erbil Unsal, Toshiyuki Kitoh, Elena Tsitsami, Mikhail Kostik, Jana Pachlopnik Schmid, Seraina Prader, Guido Laube, Despoina Maritsi, Marija Jelusic, Susan Shenoi, Sebastiaan Vastert, Gianluigi Ardissino, Randy Q. Cron, Angelo Ravelli, MAS/sJIA Working Group of the Pediatric Rheumatology European Society (PReS)
  • Health-Related Quality of Life from Adolescence to Adulthood Following Extremely Preterm Birth April 6, 2021
    To examine self-reported and parent-reported health-related quality of life (HRQL) in adults born extremely preterm compared with term-born controls and to evaluate trajectories of health status from adolescence to early adulthood.
    Yanyan Ni, Helen O’Reilly, Samantha Johnson, Neil Marlow, Dieter Wolke
  • Sex Differences in miRNA Expression and Cardiometabolic Risk Factors in Hispanic Adolescents With Obesity April 5, 2021
    To evaluate sex differences in microRNA (miRNA) expression, anthropometric measures and cardiometabolic risk factors in Hispanic adolescents with obesity.
    Genesio M. Karere, Laura A. Cox, Andrew C. Bishop, Andrew M. South, Hossam A. Shaltout, Maria-Gisela Mercado-Deane, Suzanne Cuda
  • Clinical prediction of iron deficiency at age 2: a national cross-sectional study in France April 5, 2021
    To assess the diagnostic accuracy and to develop prediction tools for iron deficiency in 2-year-old children.
    Claire Guivarch, Anne-Sylvia Sacri, Corinne Levy, Alain Bocquet, Nathanaël Lapidus, Serge Hercberg, Pascale Hebel, Anne Chevé, Christian Copin, Morched Zouari, Laurent Gouya, Mariane de Montalembert, Jérémie F. Cohen, Martin Chalumeau
  • French Pediatric Societies Call for School to Stay Open Amid the COVID-19 Pandemic April 3, 2021
    With the onset of the COVID-19 pandemic in February 2020, the majority of European countries experienced two national lockdowns, which involved school closing, imposed by goverments to control spread of the virus. In September 2020, on the reopening of the schools after the first lockdown, serious concerns were raised in Europe by scientific societies and […]
    Christèle Gras-Le Guen, Véronique Hentgen, François Dubos, Fabienne Kochert, Martine Balençon, Corinne Levy, Ido Somekh, Eli Somekh, Pietro Ferrara, Massimo Pettoello-Mantovani, Robert Cohen
  • Cardiac Manifestation Among Children with Hemolytic Uremic Syndrome April 2, 2021
    The primary objectives of the study were to describe the association between cardiac manifestations and in-hospital mortality among children with Hemolytic Uremic Syndrome (HUS).
    Emily Sanders, Clare C. Brown, Richard T. Blaszak, Brendan Crawford, Parthak Prodhan
  • Utility of MyHEARTSMAP in Youth Presenting to the Emergency Room with Mental Health Concerns April 1, 2021
    To evaluate the utility of a digital psychological self-assessment tool, MyHEARTSMAP, in youth presenting to the pediatric emergency department (ED) with a mental health concern.
    Brian CM. Li, Bruce Wright, Tyler Black, Amanda S. Newton, Quynh Doan
  • Attention Test Improvements From a Cluster Randomized Controlled Trial of Caregiver Training for HIV-Exposed/Uninfected Ugandan Preschool Children April 1, 2021
    To report vigilance attention outcomes from a cluster randomized controlled trial of early childhood development caregiver training for perinatally HIV-exposed/uninfected preschool-age children in rural Uganda. The Early Childhood Vigilance Test (ECVT) provides a webcam recording of proportion of time a child views an animation periodically moving across a computer screen.
    Joseph Ikekwere, Valentine Ucheagwu, Itziar Familiar-Lopez, Alla Sikorskii, Jorem AwaduPhD, Julius Caesar Ojuka, Deborah Givon, Cilly Shohet, Bruno Giordani, Michael J. Boivin