Protein contained in many secretions such as saliva, tears, milk and colostrum and plays a key role in the fixation and transport of iron, a process necessary for the growth and development of pathogens. It has antimicrobial activity both bactericidal and fungicidal. In association with lactic ferments it hinders the growth of pathogenic bacteria without altering the growth of normal intestinal bacterial flora.

RSS The Journal of Pediatrics

  • Center, Gestational Age, and Race Impact End-of-Life Care Practices at Regional Neonatal Intensive Care Units December 9, 2019
    To assess the impact of intercenter variation and patient factors on end-of-life care practices for infants who die in regional neonatal intensive care units (NICUs).
    Jessica T. Fry, Nana Matoba, Ankur Datta, Robert DiGeronimo, Carl H. Coghill, Girija Natarajan, Beverly Brozanski, Steven R. Leuthner, Jason Z. Niehaus, Amy Brown Schlegel, Anita Shah, Isabella Zaniletti, Thomas Bartman, Karna Murthy, Kevin M. Sullivan, Children's Hospital Neonatal Consortium (CHNC)
  • Long-Term Neurodevelopmental Outcomes in Children with Biliary Atresia December 9, 2019
    To assess long-term neurodevelopmental outcomes in school-aged children with biliary atresia.
    Lyan H. Rodijk, Anne E. den Heijer, Jan B.F. Hulscher, Behrooz Z. Alizadeh, Ruben H.J. de Kleine, Henkjan J. Verkade, Janneke L.M. Bruggink
  • Geospatial Analyses of Accessibility to Down Syndrome Specialty Care December 5, 2019
    To assess whether the location of 71 Down syndrome specialty care clinics in the US make them inaccessible to a considerable portion of the American population.
    Nicholas Joslyn, Heidi Berger, Brian G. Skotko
  • Corrigendum December 5, 2019
    In the article “Variation in Hospitalization Rates Following Emergency Department Visits in Children with Medical Complexity” by Coller et al (J Pediatr 2019; 214:113–20.e1), a middle initial was not inclulded in an author's name. The author's correct name is Christian D. Pulcini, MD, MEd, MPH.
  • Risk of Hospitalizations Following Gastrostomy in Children with Intellectual Disability December 4, 2019
    To examine the frequency of hospital admissions before and after gastrostomy insertion in children with severe intellectual disability.
    Peter Jacoby, Kingsley Wong, Preeyaporn Srasuebkul, Emma J. Glasson, David Forbes, Madhur Ravikumara, Andrew Wilson, Lakshmi Nagarajan, Jenny Bourke, Julian Trollor, Helen Leonard, Jenny Downs
  • Tracheal Tugging December 4, 2019
    A 1-month-old female patient was referred to our hospital with a history of noisy breathing and poor weight gain. The noisy breathing worsened when the patient was crying or feeding, and feeding was sometimes difficult due to respiratory distress. The patient was delivered vaginally at term with a birth weight of 2.3 kg. On examination, her […]
    Anna Otani, Kazuki Iio, Takateru Ihara
  • A Child with Whorls and Streaks: Look Beyond the Skin! December 4, 2019
    A 5-year-old-boy, born to nonconsanguineous parents, presented with global developmental delay and seizures. As a neonate, he had right focal tonic seizures and later developed asymmetric infantile spasms, generalized tonic seizures, and atypical absence seizures. He was on multiple antiepileptic drugs with only partial response. Examination showed microcephaly, right hemiparesis, and whorled hypopigmented patches over […]
    Prateek Kumar Panda, Indar Kumar Sharawat
  • Left Ventricular Dysfunction and Persistent Perfusion Abnormalities in Infants with Congenital Diaphragmatic Hernia December 4, 2019
    Congenital diaphragmatic hernia (CDH) is a complex disease that causes severe hypoxemic respiratory failure and significant morbidity and mortality.1 In the most severe cases, CDH is characterized by lung hypoplasia, severe pulmonary hypertension (PH), and cardiac dysfunction.2 Despite many advances in therapeutic options for CDH, the related PH and poor cardiac function often remain refractory […]
    Erica W. Mandell, John P. Kinsella
  • Racial Differences in the Influence of Risk Factors in Childhood on Left Ventricular Mass in Young Adulthood December 3, 2019
    To examine racial differences in the relationship between cardiovascular (CV) risk factors measured since age 10 years and left ventricular mass index (LVMI) in adulthood in the National Heart, Lung, and Blood Institute Growth and Health Study.
    Brenda Mendizábal, Philip Khoury, Jessica G. Woo, Elaine M. Urbina
  • Maternal Infection in Pregnancy and Childhood Leukemia: A Systematic Review and Meta-analysis December 3, 2019
    To summarize the published evidence regarding the association between maternal infection during pregnancy and childhood leukemia.
    Jian-Rong He, Rema Ramakrishnan, Jane E. Hirst, Audrey Bonaventure, Stephen S. Francis, Ora Paltiel, Siri E. Håberg, Stanley Lemeshow, Sjurdur Olsen, Gabriella Tikellis, Per Magnus, Michael F.G. Murphy, Joseph L. Wiemels, Martha S. Linet, Terence Dwyer